The Science Behind Mimio's Healthspan Supplement

We have a confession...

We didn't design our formulation. Thousands of years of biology did.

Activating Your Body's Built-In Longevity Mode

Turns out the fountain of youth was inside us all along! Well, not exactly, but pretty close.

Countless studies have shown that prolonged fasting is capable of profoundly enhancing our health. Promoting vitality, regeneration, and survival at the cellular level by activating our body's natural longevity pathways ^[1,2].

Fasting has been shown to:

Optimize Metabolic and Cardiovascular Health

Fasting causes a holistic shift in human metabolism that modifies our nutrient signaling pathways to maximize energy efficiency at the cellular level. This translates into whole body benefits including improvements in cardiovascular risk factors, weight management, hunger control, energy production, and inflammation.

Promote Cognitive Function and Slow Decline

Fasting has a profound effect on brain cell functionality where it helps to control neuronal excitability and neuroinflammation while enhancing neuronal growth and plasticity via increases in BDNF.

Enhance Cellular Protection

Fasting activates multiple cellular systems involved in survival and protection including key longevity-associated pathways that help to increase cell stability and stress resistance, reduce waste, protect DNA, and remove damaged cell components.

Promote Autophagy and Cellular Regeneration

Prolonged periods of fasting have been shown significantly activate autophagy, our cellular clean up and recycling system, which is responsible for the breakdown of dysfunctional proteins and organelles. Autophagy is a critical longevity-associated function that helps control mitochondrial biogenesis and functionality, senescent cell formation, metabolic efficiency, and cellular regeneration.

Extend Healthspan and Lifespan in Animal Models

Fasting is one of the most reliable methods to extend both lifespan and healthspan, the amount of time in life spent without disease or dysfunction. Lifelong intermittent fasting has been shown to extend lifespan by as much as 80% in animal models and help treat, prevent, or delay most major health issues due to its powerful effects on cellular functionality.

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The catch? It can take over 24 hours without food to start to see the full benefits of fasting. That's where Mimio comes in!

Designed From Fasting To Supercharge Your Cells

Traditional Fasting

Our Ph.D. founders spent years researching what happens in the body during prolonged fasting. They found that during a fast our body produces a unique set of bioactive molecules that are responsible for activating your cells' natural longevity pathways and helping create the benefits of fasting. The downside? It took 36 hours without food for these "fasting metabolites" to become significantly elevated, which can be... a lot.

Mimio’s Biomimetic Technology

Mimio's biomimetic formula puts a synergistic combination of those same fasting metabolites into a simple daily dose to help activate your cells' beneficial fasting pathways on demand. No fasting required. Our formulation was even able to increase lifespan in animal models by 96%!

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Science backed, clinically-validated results we're excited to share.

Read our Clinical Study

Check out our peer-reviewed clinical study to learn more about our biomimetic research, the discovery of Mimio, and how we were able to mimic the cellular effects of fasting and extend lifespan in model organisms by 96%.

Healthier Cells For a Healthier You

Mimio uses the power of daily fasting metabolites to wake up your biology and help boost your cells' natural ability to clean, repair, and protect themselves, supporting:

Balanced Cellular Inflammation
Mimio helps regulate multiple cellular inflammatory pathways to keep our immune responses balanced and help control inflammaging.

Pathways affected*: NF-KB, NLRP-3, COX 1/2, PPARs, cytokine signalling
Enhanced Stress Resistance
Mimio helps cells produce less waste and damaging free radicals while helping increase cell stability and resilience to oxidative stress and DNA damage.

Pathways affected*: Nrf-2, ERK, AMPK, PPARs, SIRTs, mitochondrial function
Cellular Clean-Up and Restoration
Mimio supports autophagy and mitophagy helping to clear damaged proteins and organelles and recycle their components into new functional versions.

Pathways affected*: mTOR, AKT, HATs, AMPK, SIRTs, mitochondrial function
Optimized Metabolism
Mimio supports mitochondrial health and biogenesis and helps regulate cellular fasting pathways that optimize energy efficiency, reduce waste, and promote fat metabolism.

Pathways affected*: AKT, P13K, AMPK, SIRT/NAD+, PPARs, mitophagy
Healthy Aging
Mimio targets multiple cellular pathways and processes associated with increased longevity, helping your cells restore and maintain their function as they age (slower).

Pathways affected*: mTOR, AKT, AMPK, SIRT/NAD+, PPARs, ERK, NrF-2, mitochondrial biogenesis, autophagy

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Allow Us to Introduce Yourself.

The ingredients in Mimio's biomimetic formulation are naturally elevated in the body during a 36 hour fast, validated in over 100 clinical studies, and work together to help optimize your health at a cellular level.

Spermidine

Made from the breakdown of amino acids in your body, spermidine is a powerhouse of cellular protection and repair. It’s been shown to support cellular autophagy, mitochondrial health, cognition, and healthy aging.*

Read Studies about Spermidine

Oleoylethanolamide

Made from healthy fats in your body, OEA is a cellular metabolic supercharger. It’s been clinically shown to help control hunger and cravings, support metabolic health, help balance dietary inflammation, and support healthy body composition.*

Read Studies about Oleoylethanolamide

Palmitoylethanolamide

PEA is a natural endocannabinoid produced by the body that helps cells rest, relax, and recover from stress. It’s been clinically shown to help support mood, relief of everyday discomfort, sleep quality, and balanced immune responses.*

Read Studies about Palmitoylethanolamide

Nicotinamide

A naturally occurring vitamin derivative, nicotinamide is a key component of cellular energy balance and production. It’s been clinically shown to support heart, muscle, and skin health and help boost cellular NAD+ levels.*

Read Studies about Nicotinamide